Psilocybin, along with certain other psychedelics, has been shown to help increase concentration, energy, creativity, mood, motivation, empathy, and even physical improvements such as stamina and reflexes. Psilocybin and psychedelics, in general, have been shown to help people overcome addictions and lessen anxiety. Microdosing has been shown to help lower the fight or flight mode responses in people. This helps to process emotions and thoughts, including past trauma and difficult memories or struggles. Psilocybin allows us to analyze ourselves and our emotions in a safer more enlightened sense to allow for new ways to overcome difficult negative or emotional experiences. Psilocybin works by stimulating a serotonin receptor called 5-HT2A. This causes 2 main things to occur in the brain:
1. BDNF (Brain-Derived Neurotrophic Factor) starts to be produced more in the brain which helps stimulate growth, connections, and activity in the brain.
2. Glutamate, a neurotransmitter, starts to increase transmission which is responsible for brain functions like cognition, learning, and memory.
Psilocybin also causes different brain connections which are formed by dampening the activity of the DMN (Default Mode Network). DMN is linked to many different mental activities such as day-dreaming, self-reflection, and thoughts of the past or future. Studies have shown that overactive DMN could be linked to Depression. This shows how Psilocybin can help battle depression, anxiety, and make connections that allow for more creative thoughts and introspection.